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Progressive Familial Intrahepatic Cholestatsis (PFIC)

PFIC is the name which has been given to a group of inherited conditions causing cholestasis (reduced bile flow) in children. 

The bile flow is reduced either because the liver cannot make bile properly or because it cannot get it out of the liver cells into the bile ducts, or both. The bile ducts themselves may also be abnormal reducing the flow of bile through them.

Recent research has led to a better understanding of these conditions but the research is still continuing.

CLDF has a detailed leaflet on PFIC.  Order a copy from the online shop.

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